CD4(+) T Cells from CD4C/HIV(Nef) Transgenic Mice Show Enhanced Activation In Vivo with Impaired Proliferation In Vitro but Are Dispensable for the Development of a Severe AIDS-Like Organ Disease

Registos relacionados

• The Nef-Mediated AIDS-Like Disease of CD4C/Human Immunodeficiency Virus Transgenic Mice Is Associated with Increased Fas/FasL Expression on T Cells and T-Cell Death but Is Not Prevented in Fas-, FasL-, Tumor Necrosis Factor Receptor 1-, or Interleukin-1β-Converting Enzyme-Deficient or Bcl2-Expressing Transgenic Mice
  Por: Priceputu, Elena, et al.
  Publicado em: (2005)
• The AIDS-Like Disease of CD4C/Human Immunodeficiency Virus Transgenic Mice Is Associated with Accumulation of Immature CD11b(Hi) Dendritic Cells
  Por: Poudrier, Johanne, et al.
  Publicado em: (2003)
• The Pathogenicity of Human Immunodeficiency Virus (HIV) Type 1 Nef in CD4C/HIV Transgenic Mice Is Abolished by Mutation of Its SH3-Binding Domain, and Disease Development Is Delayed in the Absence of Hck
  Por: Hanna, Zaher, et al.
  Publicado em: (2001)
• Adult AIDS-Like Disease in a Novel Inducible Human Immunodeficiency Virus Type 1 Nef Transgenic Mouse Model: CD4(+) T-Cell Activation Is Nef Dependent and Can Occur in the Absence of Lymphophenia
  Por: Rahim, Mir Munir Ahmed, et al.
  Publicado em: (2009)
• Primary Human Immunodeficiency Virus Type 1 Nef Alleles Show Major Differences in Pathogenicity in Transgenic Mice
  Por: Priceputu, Elena, et al.
  Publicado em: (2007)