Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity.
An abnormal isoform of the prion protein (PrP) designated PrPSc is the major, or possibly the only, component of infectious prions. Structural studies of PrPSc have been impeded by its lack of solubility under conditions in which infectivity is retained. Among the many detergents examined, only trea...
Sábháilte in:
| Foilsithe in: | J Virol |
|---|---|
| Príomhchruthaitheoirí: | , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
American Society for Microbiology (ASM)
1996
|
| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189995/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627692/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1714-1722.1996 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
|