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Specific Role of Chk1 Phosphorylations in Cell Survival and Checkpoint Activation

Chk1 is a multifunctional protein kinase that plays essential roles in cell survival and cell cycle checkpoints. Chk1 is phosphorylated at multiple sites by several protein kinases, but the precise effects of these phosphorylations are largely unknown. Using a knockout-knockin system, we examined th...

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Detalhes bibliográficos
Main Authors: Niida, Hiroyuki, Katsuno, Yuko, Banerjee, Birendranath, Hande, M. Prakash, Nakanishi, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899884/
https://ncbi.nlm.nih.gov/pubmed/17242188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01611-06
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