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Specific Role of Chk1 Phosphorylations in Cell Survival and Checkpoint Activation
Chk1 is a multifunctional protein kinase that plays essential roles in cell survival and cell cycle checkpoints. Chk1 is phosphorylated at multiple sites by several protein kinases, but the precise effects of these phosphorylations are largely unknown. Using a knockout-knockin system, we examined th...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1899884/ https://ncbi.nlm.nih.gov/pubmed/17242188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01611-06 |
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