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Specific Role of Chk1 Phosphorylations in Cell Survival and Checkpoint Activation

Chk1 is a multifunctional protein kinase that plays essential roles in cell survival and cell cycle checkpoints. Chk1 is phosphorylated at multiple sites by several protein kinases, but the precise effects of these phosphorylations are largely unknown. Using a knockout-knockin system, we examined th...

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Bibliografische gegevens
Hoofdauteurs: Niida, Hiroyuki, Katsuno, Yuko, Banerjee, Birendranath, Hande, M. Prakash, Nakanishi, Makoto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899884/
https://ncbi.nlm.nih.gov/pubmed/17242188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01611-06
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