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High donor FOXP3-positive regulatory T-cell (T(reg)) content is associated with a low risk of GVHD following HLA-matched allogeneic SCT
Regulatory T cells (T(reg)s) that constitutively express FOXP3 are instrumental to the maintenance of tolerance and may suppress graft-versus-host disease (GVHD) in humans. To determine whether regulatory T cells in allogeneic stem cell transplants (SCTs) ameliorate GVHD after transplantation, we qu...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society of Hematology
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895877/ https://ncbi.nlm.nih.gov/pubmed/16627754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-003996 |
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