Deficient CD4(+) CD25(+) FOXP3(+) T regulatory cells in acquired aplastic anemia

Regulatory T cells are believed to control the development and progression of autoimmunity by suppressing autoreactive T cells. Decreased numbers of CD4(+)CD25(+) FOXP3(+) T cells (Tregs) are associated with impaired immune homeostasis and development of autoimmune diseases. The transcription factor...

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Bibliographic Details
Main Authors: Solomou, Elena E., Rezvani, Katayoun, Mielke, Stephan, Malide, Daniela, Keyvanfar, Keyvan, Visconte, Valeria, Kajigaya, Sachiko, Barrett, A. John, Young, Neal S.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2007
Subjects:
Immunobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1975843/
https://ncbi.nlm.nih.gov/pubmed/17463169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-066258
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