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T-bet, a Th1 transcription factor, is up-regulated in T cells from patients with aplastic anemia
In aplastic anemia, immune destruction of hematopoietic cells results in bone marrow failure. Type 1 cytokines, especially IFN-γ, have been implicated in the pathophysiology of T-cell–mediated, Fas-mediated stem cell apoptosis of hematopoietic cells. Here, we show that the transcription factor T-bet...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society of Hematology
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895294/ https://ncbi.nlm.nih.gov/pubmed/16434488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-10-4201 |
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