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The role of the Th1 transcription factor T-bet in a mouse model of immune-mediated bone-marrow failure

The transcription factor T-bet is a key regulator of type 1 immune responses. We examined the role of T-bet in an animal model of immune-mediated bone marrow (BM) failure using mice carrying a germline T-bet gene deletion (T-bet(−/−)). In comparison with normal C57BL6 (B6) control mice, T-bet(−/−) m...

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Bibliografski detalji
Glavni autori: Tang, Yong, Desierto, Marie J., Chen, Jichun, Young, Neal S.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810980/
https://ncbi.nlm.nih.gov/pubmed/19903901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-211383
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