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The role of the Th1 transcription factor T-bet in a mouse model of immune-mediated bone-marrow failure
The transcription factor T-bet is a key regulator of type 1 immune responses. We examined the role of T-bet in an animal model of immune-mediated bone marrow (BM) failure using mice carrying a germline T-bet gene deletion (T-bet(−/−)). In comparison with normal C57BL6 (B6) control mice, T-bet(−/−) m...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810980/ https://ncbi.nlm.nih.gov/pubmed/19903901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-211383 |
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