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PPARγ antagonist attenuates mouse immune-mediated bone marrow failure by inhibition of T cell function
Acquired aplastic anemia is an immune-mediated disease, in which T cells target hematopoietic cells; at presentation, the bone marrow is replaced by fat. It was reported that bone marrow adipocytes were negative regulators of hematopoietic microenvironment. To examine the role of adipocytes in bone...
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| Udgivet i: | Haematologica |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Ferrata Storti Foundation
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4697892/ https://ncbi.nlm.nih.gov/pubmed/26589913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.121632 |
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