Ezh2 regulates transcriptional and post-translational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice()

Acquired aplastic anemia (AA) is a potentially fatal bone marrow (BM) failure syndrome. IFN-γ-producing T helper (Th)1 CD4(+) T cells mediate the immune destruction of hematopoietic cells, and are central to the pathogenesis. However, the molecular events that control the development of BM-destructi...

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Detalhes bibliográficos
Main Authors: Tong, Qing, He, Shan, Xie, Fang, Mochizuki, Kazuhiro, Liu, Yongnian, Mochizuki, Izumi, Meng, Lijun, Sun, Hongxing, Zhang, Yanyun, Guo, Yajun, Hexner, Elizabeth, Zhang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075972/
https://ncbi.nlm.nih.gov/pubmed/24760151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302943
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