The histone methyltransferase Ezh2 is a crucial epigenetic regulator of allogeneic T-cell responses mediating graft-versus-host disease

Posttranscriptional modification of histones by methylation plays an important role in regulating Ag-driven T-cell responses. We have recently drawn correlations between allogeneic T-cell responses and the histone methyltransferase Ezh2, which catalyzes histone H3 lysine 27 trimethylation. The funct...

Full description

Saved in:
Bibliographic Details
Main Authors: He, Shan, Xie, Fang, Liu, Yongnian, Tong, Qing, Mochizuki, Kazuhiro, Lapinski, Philip E., Mani, Ram-Shankar, Reddy, Pavan, Mochizuki, Izumi, Chinnaiyan, Arul M., Mineishi, Shin, King, Philip D., Zhang, Yi
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2013
Subjects:
Transplantation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862282/
https://ncbi.nlm.nih.gov/pubmed/24141370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-05-505180
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items