The histone methyltransferase Ezh2 is a crucial epigenetic regulator of allogeneic T-cell responses mediating graft-versus-host disease

Posttranscriptional modification of histones by methylation plays an important role in regulating Ag-driven T-cell responses. We have recently drawn correlations between allogeneic T-cell responses and the histone methyltransferase Ezh2, which catalyzes histone H3 lysine 27 trimethylation. The funct...

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Détails bibliographiques
Auteurs principaux: He, Shan, Xie, Fang, Liu, Yongnian, Tong, Qing, Mochizuki, Kazuhiro, Lapinski, Philip E., Mani, Ram-Shankar, Reddy, Pavan, Mochizuki, Izumi, Chinnaiyan, Arul M., Mineishi, Shin, King, Philip D., Zhang, Yi
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2013
Sujets:
Transplantation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862282/
https://ncbi.nlm.nih.gov/pubmed/24141370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-05-505180
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