Rabbit ATG but not horse ATG promotes expansion of functional CD4(+)CD25(high)FOXP3(+) regulatory T cells in vitro

Regulatory T cells (Treg) play important roles in suppressing immune responses and maintaining tolerance. Rabbit antithymocyte globulin (rATG) and horse ATG (hATG) are widely used in the treatment of immune-mediated syndromes, but their effects on Treg are unknown. We show here that in vitro culture...

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Autores principales: Feng, Xingmin, Kajigaya, Sachiko, Solomou, Elena E., Keyvanfar, Keyvan, Xu, Xiuli, Raghavachari, Nalini, Munson, Peter J., Herndon, Thomas M., Chen, Jichun, Young, Neal S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2008
Materias:
Immunobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275026/
https://ncbi.nlm.nih.gov/pubmed/18250226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-130146
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