Graft-versus-leukemia effects associated with detectable Wilms tumor-1–specific T lymphocytes after allogeneic stem-cell transplantation for acute lymphoblastic leukemia

To determine whether the leukemia-associated Wilms tumor antigen (WT1) contributes to a graft-versus-leukemia (GVL) effect after allogeneic stem-cell transplantation (SCT) for acute lymphoblastic leukemia (ALL), we studied CD8(+) T-cell responses to WT1 in 10 human lymphocyte antigen (HLA)–A*0201–po...

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Autores principales: Rezvani, Katayoun, Yong, Agnes S. M., Savani, Bipin N., Mielke, Stephan, Keyvanfar, Keyvan, Gostick, Emma, Price, David A., Douek, Daniel C., Barrett, A. John
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2007
Materias:
Immunobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976363/
https://ncbi.nlm.nih.gov/pubmed/17505014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-03-076844
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