High donor FOXP3-positive regulatory T-cell (T(reg)) content is associated with a low risk of GVHD following HLA-matched allogeneic SCT

Regulatory T cells (T(reg)s) that constitutively express FOXP3 are instrumental to the maintenance of tolerance and may suppress graft-versus-host disease (GVHD) in humans. To determine whether regulatory T cells in allogeneic stem cell transplants (SCTs) ameliorate GVHD after transplantation, we qu...

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Autori principali: Rezvani, Katayoun, Mielke, Stephan, Ahmadzadeh, Mojgan, Kilical, Yasemin, Savani, Bipin N., Zeilah, Josette, Keyvanfar, Keyvan, Montero, Aldemar, Hensel, Nancy, Kurlander, Roger, Barrett, A. John
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Hematology 2006
Soggetti:
Immunobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895877/
https://ncbi.nlm.nih.gov/pubmed/16627754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-003996
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