Reconstitution of FOXP3(+) regulatory T cells (T(regs)) after CD25-depleted allotransplantion in elderly patients and association with acute graft-versus-host disease

Selective depletion (SD) of host-reactive donor T cells from allogeneic stem-cell transplants (SCTs) using an anti-CD25 immunotoxin (IT) is a strategy to prevent acute graft-versus-host disease (aGvHD). There is concern that concurrent removal of regulatory T cells (T(regs)) with incomplete removal...

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Bibliografiset tiedot
Päätekijät: Mielke, Stephan, Rezvani, Katayoun, Savani, Bipin N., Nunes, Raquel, Yong, Agnes S. M., Schindler, John, Kurlander, Roger, Ghetie, Victor, Read, Elizabeth J., Solomon, Scott R., Vitetta, Ellen S., Barrett, A. John
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2007
Aiheet:
Transplantation
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1975850/
https://ncbi.nlm.nih.gov/pubmed/17478639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-03-079160
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