Selective depletion of alloreactive donor lymphocytes: a novel method to reduce the severity of graft-versus-host disease in older patients undergoing matched sibling donor stem cell transplantation

We have selectively depleted host-reactive donor T cells from peripheral blood stem cell (PBSC) transplant allografts ex vivo using an anti-CD25 immunotoxin. We report a clinical trial to decrease graft-versus-host disease (GVHD) in elderly patients receiving selectively depleted PBSC transplants fr...

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Библиографические подробности
Главные авторы: Solomon, Scott R., Mielke, Stephan, Savani, Bipin N., Montero, Aldemar, Wisch, Laura, Childs, Richard, Hensel, Nancy, Schindler, John, Ghetie, Victor, Leitman, Susan F., Mai, Thao, Carter, Charles S., Kurlander, Roger, Read, Elizabeth J., Vitetta, Ellen S., Barrett, A. John
Формат: Artigo
Язык:Inglês
Опубликовано: © 2005 by The American Society of Hematology 2005
Предметы:
Transplantation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895160/
https://ncbi.nlm.nih.gov/pubmed/15817673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0393
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