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Adenosine A2a receptors induce heterologous desensitization of chemokine receptors

Adenosine, released by cells in an injurious or hypoxic environment, possesses potent anti-inflammatory effects by inhibiting the production of proinflammatory cytokines and superoxide anions (O(2) (-)). We hypothesized that adenosine compounds also induced heterologous desensitization of chemokine...

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Dettagli Bibliografici
Autori principali: Zhang, Ning, Yang, De, Dong, Huifang, Chen, Qian, Dimitrova, Dessislava I., Rogers, Thomas J., Sitkovsky, Michail, Oppenheim, Joost J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Hematology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895822/
https://ncbi.nlm.nih.gov/pubmed/16522819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2599
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