Heterologous desensitization of opioid receptors by chemokines inhibits chemotaxis and enhances the perception of pain

The chemokines use G protein-coupled receptors to regulate the migratory and proadhesive responses of leukocytes. Based on observations that G protein-coupled receptors undergo heterologous desensitization, we have examined the ability of chemokines to also influence the perception of pain by cross-...

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Autors principals: Szabo, Imre, Chen, Xiao-Hong, Xin, Li, Adler, Martin W., Howard, O. M. Z., Oppenheim, Joost J., Rogers, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC124904/
https://ncbi.nlm.nih.gov/pubmed/12130663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102327699
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