RAPID HETEROLOGOUS DESENSITIZATION OF ANTINOCICEPTIVE ACTIVITY BETWEEN MU OR DELTA OPIOID RECEPTORS AND CHEMOKINE RECEPTORS IN RATS

Previous studies have shown pretreatment with chemokines CCL5/RANTES (100 ng) or CXCL12/SDF-1alpha (100 ng) injected into the periaqueductal grey (PAG) region of the brain, 30 minutes (min) before the mu opioid agonist DAMGO (400 ng), blocked the antinociception induced by DAMGO in the in vivo cold...

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Detalhes bibliográficos
Main Authors: Chen, Xiaohong, Geller, Ellen B., Rogers, Thomas J., Adler, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1880888/
https://ncbi.nlm.nih.gov/pubmed/17049756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2006.09.010
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