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RAPID HETEROLOGOUS DESENSITIZATION OF ANTINOCICEPTIVE ACTIVITY BETWEEN MU OR DELTA OPIOID RECEPTORS AND CHEMOKINE RECEPTORS IN RATS

Previous studies have shown pretreatment with chemokines CCL5/RANTES (100 ng) or CXCL12/SDF-1alpha (100 ng) injected into the periaqueductal grey (PAG) region of the brain, 30 minutes (min) before the mu opioid agonist DAMGO (400 ng), blocked the antinociception induced by DAMGO in the in vivo cold...

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Bibliografiske detaljer
Main Authors: Chen, Xiaohong, Geller, Ellen B., Rogers, Thomas J., Adler, Martin W.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1880888/
https://ncbi.nlm.nih.gov/pubmed/17049756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2006.09.010
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