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Nociceptin/orphanin FQ blocks the antinociception induced by mu, kappa and delta opioid agonists on the cold water tail-flick test

Nociceptin/orphanin FQ (N/OFQ), a 17-amino-acid peptide, is an endogenous agonist whose receptor is similar in sequence to mu, delta and kappa opioid receptors. It has been reported that N/OFQ can block antinociceptive effects induced by opioid receptor agonists in the radiant heat tail-flick test a...

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Main Authors: Chen, Xiaohong, Geller, Ellen B., Adler, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1859853/
https://ncbi.nlm.nih.gov/pubmed/17173891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2006.11.001
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