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Long-lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112

Chemical modifications of nociceptin/orphanin FQ (N/OFQ) peptide that result in increased potency and resistance to degradation have recently lead to the discovery of [(pF)Phe(4)Aib(7)Arg(14)Lys(15)]N/OFQ-NH(2) (UFP-112), a novel N/OFQ peptide (NOP) receptor agonist. The aim of this study was to inv...

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Detalhes bibliográficos
Main Authors: Hu, Eric, Calò, Girolamo, Guerrini, Remo, Ko, Mei-Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861283/
https://ncbi.nlm.nih.gov/pubmed/19945794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2009.10.026
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