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UFP‐112 a Potent and Long‐Lasting Agonist Selective for the Nociceptin/Orphanin FQ Receptor

Nociceptin/orphanin FQ (N/OFQ) controls several biological functions via selective activation of the N/OFQ peptide receptor (NOP). [(pF)Phe(4)Aib(7)Arg(14)Lys(15)]N/OFQ‐NH(2) (UFP‐112) is an NOP receptor ligand designed using a combination of several chemical modifications in the same peptide sequen...

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Publicat a:CNS Neurosci Ther
Autors principals: Calo', Girolamo, Rizzi, Anna, Cifani, Carlo, Di Bonaventura, Maria Vittoria Micioni, Regoli, Domenico, Massi, Maurizio, Salvadori, Severo, Lambert, David G., Guerrini, Remo
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493780/
https://ncbi.nlm.nih.gov/pubmed/20497197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-5949.2009.00107.x
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