[Nphe(1),Arg(14),Lys(15)]Nociceptin-NH(2), a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor

1. Nociceptin/orphanin FQ (N/OFQ) modulates several biological functions by activating a specific G-protein coupled receptor (NOP). Few molecules are available that selectively activate or block the NOP receptor. Here we describe the in vitro and in vivo pharmacological profile of a novel NOP recept...

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Autors principals: Calo, Girolamo, Rizzi, Anna, Rizzi, Daniela, Bigoni, Raffaella, Guerrini, Remo, Marzola, Giuliano, Marti, Matteo, McDonald, John, Morari, Michele, Lambert, David G, Salvadori, Severo, Regoli, Domenico
Format: Artigo
Idioma:Inglês
Publicat: 2002
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Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573345/
https://ncbi.nlm.nih.gov/pubmed/12010780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704706
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