Protein Kinase Cζ Mediates μ-Opioid Receptor-induced Cross-desensitization of Chemokine Receptor CCR5

We have previously shown that the μ-opioid receptor (MOR) is capable of mediating cross-desensitization of several chemokine receptors including CCR5, but the biochemical mechanism of this process has not been fully elucidated. We have carried out a series of functional and biochemical studies and f...

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Autori principali: Song, Changcheng, Rahim, Rahil T., Davey, Penelope C., Bednar, Filip, Bardi, Giuseppe, Zhang, Lily, Zhang, Ning, Oppenheim, Joost J., Rogers, Thomas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121462/
https://ncbi.nlm.nih.gov/pubmed/21454526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177303
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