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Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues

In vitro studies have implicated chemokine receptors in consumption and clearance of specific ligands. We studied the role that various signaling chemokine receptors play during ligand homeostasis in vivo. We examined the levels of ligands in serum and CNS tissue in mice lacking chemokine receptors....

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Detalhes bibliográficos
Main Authors: Cardona, Astrid E., Sasse, Margaret E., Liu, Liping, Cardona, Sandra M., Mizutani, Makiko, Savarin, Carine, Hu, Taofang, Ransohoff, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442740/
https://ncbi.nlm.nih.gov/pubmed/18347198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-10-118497
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