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Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells

Retroviruses can induce hematopoietic disease via insertional mutagenesis of cancer genes and provide valuable molecular tags for cancer gene discovery. Here we show that insertional mutagenesis can also identify genes that promote the immortalization of hematopoietic cells, which normally have only...

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Detalhes bibliográficos
Main Authors: Du, Yang, Jenkins, Nancy A., Copeland, Neal G.
Formato: Artigo
Idioma:Inglês
Publicado em: © 2005 by The American Society of Hematology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895096/
https://ncbi.nlm.nih.gov/pubmed/16109773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1113
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