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Cooperating cancer-gene identification through oncogenic-retrovirus–induced insertional mutagenesis

Multiple cooperating mutations that deregulate different signaling pathways are required to induce cancer. Identifying these cooperating mutations is a prerequisite for developing better combinatorial therapies for treating cancer. Here we show that cooperating cancer mutations can be identified thr...

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Bibliografiske detaljer
Main Authors: Du, Yang, Spence, Sally E., Jenkins, Nancy A., Copeland, Neal G.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Hematology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895273/
https://ncbi.nlm.nih.gov/pubmed/15961513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-12-4840
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