Setbp1 promotes the self-renewal of murine myeloid progenitors via activation of Hoxa9 and Hoxa10

Acquisition of self-renewal capability by myeloid progenitors to become leukemic stem cells during myeloid leukemia development is poorly understood. Here, we show that Setbp1 overexpression efficiently confers self-renewal capability to myeloid progenitors in vitro, causing their immortalization in...

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Detalhes bibliográficos
Main Authors: Oakley, Kevin, Han, Yufen, Vishwakarma, Bandana A., Chu, Su, Bhatia, Ravi, Gudmundsson, Kristbjorn O., Keller, Jonathan, Chen, Xiongfong, Vasko, Vasyl, Jenkins, Nancy A., Copeland, Neal G., Du, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383018/
https://ncbi.nlm.nih.gov/pubmed/22566606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-10-388710
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