Prdm16 is a critical regulator of adult long-term hematopoietic stem cell quiescence

Regulation of quiescence is critical for the maintenance of adult hematopoietic stem cells (HSCs). Disruption of transcription factor gene Prdm16 during mouse embryonic development has been shown to cause a severe loss of fetal liver HSCs; however, the underlying mechanisms and the function of Prdm1...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gudmundsson, Kristbjorn O., Nguyen, Nhu, Oakley, Kevin, Han, Yufen, Gudmundsdottir, Bjorg, Liu, Pentao, Tessarollo, Lino, Jenkins, Nancy A., Copeland, Neal G., Du, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749346/
https://ncbi.nlm.nih.gov/pubmed/33268499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017626117
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