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Prdm16 is a critical regulator of adult long-term hematopoietic stem cell quiescence
Regulation of quiescence is critical for the maintenance of adult hematopoietic stem cells (HSCs). Disruption of transcription factor gene Prdm16 during mouse embryonic development has been shown to cause a severe loss of fetal liver HSCs; however, the underlying mechanisms and the function of Prdm1...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7749346/ https://ncbi.nlm.nih.gov/pubmed/33268499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017626117 |
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