Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress

The transcription factor Meis1 is expressed preferentially in hematopoietic stem cells (HSCs) and overexpressed in certain leukemias. However, the functions of Meis1 in hematopoiesis remain largely unknown. In the present study, we found that Meis1 is required for the maintenance of hematopoiesis un...

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Autori principali: Unnisa, Zeenath, Clark, Jason P., Roychoudhury, Jayeeta, Thomas, Elizabeth, Tessarollo, Lino, Copeland, Neal G., Jenkins, Nancy A., Grimes, H. Leighton, Kumar, Ashish R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2012
Soggetti:
Hematopoiesis and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525022/
https://ncbi.nlm.nih.gov/pubmed/23091297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-435800
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