Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress

The transcription factor Meis1 is expressed preferentially in hematopoietic stem cells (HSCs) and overexpressed in certain leukemias. However, the functions of Meis1 in hematopoiesis remain largely unknown. In the present study, we found that Meis1 is required for the maintenance of hematopoiesis un...

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Hlavní autoři: Unnisa, Zeenath, Clark, Jason P., Roychoudhury, Jayeeta, Thomas, Elizabeth, Tessarollo, Lino, Copeland, Neal G., Jenkins, Nancy A., Grimes, H. Leighton, Kumar, Ashish R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2012
Témata:
Hematopoiesis and Stem Cells
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525022/
https://ncbi.nlm.nih.gov/pubmed/23091297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-435800
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