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Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells

The role of Meis1 in leukemia is well established, but its role in hematopoietic stem cells (HSCs) remains poorly understood. Previously, we showed that HSCs use glycolytic metabolism to meet their energy demands. However, the mechanism of regulation of HSC metabolism, and the importance of maintain...

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Autores principales: Kocabas, Fatih, Zheng, Junke, Thet, Suwannee, Copeland, Neal G., Jenkins, Nancy A., DeBerardinis, Ralph J., Zhang, Chengcheng, Sadek, Hesham A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525021/
https://ncbi.nlm.nih.gov/pubmed/22995899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-432260
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