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Profilin 1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrow
How stem cells interact with the microenvironment to regulate their cell fates and metabolism is largely unknown. Here we demonstrated that the deletion of the cytoskeleton-modulating protein profilin 1 (pfn1) in hematopoietic stem cell (HSCs) led to bone marrow failure, loss of quiescence, and mobi...
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| Main Authors: | , , , , , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society of Hematology
2014
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3924932/ https://ncbi.nlm.nih.gov/pubmed/24385538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-04-498469 |
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