Hypoxic metabolism in human hematopoietic stem cells

BACKGROUND: Adult hematopoietic stem cells (HSCs) are maintained in a microenvironment, known as niche in the endosteal regions of the bone marrow. This stem cell niche with low oxygen tension requires HSCs to adopt a unique metabolic profile. We have recently demonstrated that mouse long-term hemat...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Kocabas, Fatih, Xie, Li, Xie, Jingjing, Yu, Zhuo, DeBerardinis, Ralph J., Kimura, Wataru, Thet, SuWannee, Elshamy, Ahmed F., Abouellail, Hesham, Muralidhar, Shalini, Liu, Xiaoye, Chen, Chiqi, Sadek, Hesham A., Zhang, Cheng Cheng, Zheng, Junke
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517642/
https://ncbi.nlm.nih.gov/pubmed/26221532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0020-3
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