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Angiopoietin-like protein 3 supports the activity of hematopoietic stem cells in the bone marrow niche
The physiologic roles of angiopoietin-like proteins (Angptls) in the hematopoietic system remain unknown. Here we show that hematopoietic stem cells (HSCs) in Angptl3-null mice are decreased in number and quiescence. HSCs transplanted into Angptl3-null recipient mice exhibited impaired repopulation....
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031476/ https://ncbi.nlm.nih.gov/pubmed/20959605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-291716 |
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