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Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantation

Hematopoietic stem cells (HSCs) are the basis of bone marrow transplantation and are attractive target cells for hematopoietic gene therapy, but these important clinical applications have been severely hampered by difficulties in ex vivo expansion of HSCs. In particular, the use of cord blood for ad...

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Detalhes bibliográficos
Main Authors: Zhang, Cheng Cheng, Kaba, Megan, Iizuka, Satoru, Huynh, HoangDinh, Lodish, Harvey F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275010/
https://ncbi.nlm.nih.gov/pubmed/18202223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-122119
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