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Angiopoietin-like protein 3 supports the activity of hematopoietic stem cells in the bone marrow niche

The physiologic roles of angiopoietin-like proteins (Angptls) in the hematopoietic system remain unknown. Here we show that hematopoietic stem cells (HSCs) in Angptl3-null mice are decreased in number and quiescence. HSCs transplanted into Angptl3-null recipient mice exhibited impaired repopulation....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zheng, Junke, Huynh, HoangDinh, Umikawa, Masato, Silvany, Robert, Zhang, Cheng Cheng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031476/
https://ncbi.nlm.nih.gov/pubmed/20959605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-291716
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