Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells

The role of Meis1 in leukemia is well established, but its role in hematopoietic stem cells (HSCs) remains poorly understood. Previously, we showed that HSCs use glycolytic metabolism to meet their energy demands. However, the mechanism of regulation of HSC metabolism, and the importance of maintain...

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Detalhes bibliográficos
Main Authors: Kocabas, Fatih, Zheng, Junke, Thet, Suwannee, Copeland, Neal G., Jenkins, Nancy A., DeBerardinis, Ralph J., Zhang, Chengcheng, Sadek, Hesham A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525021/
https://ncbi.nlm.nih.gov/pubmed/22995899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-432260
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