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High-dose factor VIII inhibits factor VIII–specific memory B cells in hemophilia A with factor VIII inhibitors
Hemophilia A in its severe form is a life-threatening hemorrhagic disease that is caused by mutations in the factor VIII (FVIII) gene (symbol F8). About 25% of patients who receive replacement therapy develop neutralizing antibodies that inhibit the function of substituted FVIII. Long-term applicati...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The American Society of Hematology
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895061/ https://ncbi.nlm.nih.gov/pubmed/16091456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1182 |
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