High-dose factor VIII inhibits factor VIII–specific memory B cells in hemophilia A with factor VIII inhibitors

Hemophilia A in its severe form is a life-threatening hemorrhagic disease that is caused by mutations in the factor VIII (FVIII) gene (symbol F8). About 25% of patients who receive replacement therapy develop neutralizing antibodies that inhibit the function of substituted FVIII. Long-term applicati...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hausl, Christina, Ahmad, Rafi U., Sasgary, Maria, Doering, Christopher B., Lollar, Pete, Richter, Günter, Schwarz, Hans Peter, Turecek, Peter L., Reipert, Birgit M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895061/
https://ncbi.nlm.nih.gov/pubmed/16091456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1182
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados