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Reversion of a Moloney murine leukemia virus RNase H mutant at a second site restores enzyme function and infectivity.

The reverse transcriptase of retroviruses contains an RNase H activity essential for the proper synthesis of the viral DNA copy of the RNA genome. We have previously characterized a number of point mutations altering the RNase domain of the Moloney murine leukemia virus reverse transcriptase (S. W....

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Blain, S W, Hendrickson, W A, Goff, S P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 1995
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189329/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7541847/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.8.5113-5116.1995
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