Reversion of a Moloney murine leukemia virus RNase H mutant at a second site restores enzyme function and infectivity.

The reverse transcriptase of retroviruses contains an RNase H activity essential for the proper synthesis of the viral DNA copy of the RNA genome. We have previously characterized a number of point mutations altering the RNase domain of the Moloney murine leukemia virus reverse transcriptase (S. W....

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Blain, S W, Hendrickson, W A, Goff, S P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189329/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7541847/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.8.5113-5116.1995
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