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Reversion of a Moloney murine leukemia virus RNase H mutant at a second site restores enzyme function and infectivity.

The reverse transcriptase of retroviruses contains an RNase H activity essential for the proper synthesis of the viral DNA copy of the RNA genome. We have previously characterized a number of point mutations altering the RNase domain of the Moloney murine leukemia virus reverse transcriptase (S. W....

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Autors principals: Blain, S W, Hendrickson, W A, Goff, S P
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC189329/
https://ncbi.nlm.nih.gov/pubmed/7541847
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