Reversion of a Moloney murine leukemia virus RNase H mutant at a second site restores enzyme function and infectivity.
The reverse transcriptase of retroviruses contains an RNase H activity essential for the proper synthesis of the viral DNA copy of the RNA genome. We have previously characterized a number of point mutations altering the RNase domain of the Moloney murine leukemia virus reverse transcriptase (S. W....
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1995
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189329/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7541847/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.8.5113-5116.1995 |
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