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Collagen Type II-Specific Monoclonal Antibody-Induced Arthritis in Mice : Description of the Disease and the Influence of Age, Sex, and Genes

Transfer of collagen type II (CII)-specific monoclonal antibodies induces an acute form of arthritis (collagen type II antibody-induced arthritis, CAIA) in naïve mice. Arthritis was induced using a pair of monoclonal antibodies M2139 and CIIC1, binding to J1 and C1(I) epitopes of CII, respectively....

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Autors principals: Nandakumar, Kutty Selva, Svensson, Lars, Holmdahl, Rikard
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892447/
https://ncbi.nlm.nih.gov/pubmed/14578183
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