Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis

During the development of rheumatoid arthritis (RA) autoantibodies to IgG-Fc, citrullinated proteins, collagen type II (CII), glucose 6 phosphoisomerase (G6PI) and some other self-antigens appear. Of these, a pathogenic effect of the anti-CII and anti-G6PI antibodies is well demonstrated using anima...

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Bibliographic Details
Main Authors: Nandakumar, Kutty Selva, Holmdahl, Rikard
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794524/
https://ncbi.nlm.nih.gov/pubmed/17254316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2089
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