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Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity

Joint cartilage is attacked in both autoimmune inflammatory and osteoarthritic processes. Type IX collagen (CIX) is a protein of importance for cartilage integrity and stability. In this study we have backcrossed a transgenic disruption of the col9a1 gene, which leads to an absence of CIX, into two...

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Main Authors: Carlsen, Stefan, Nandakumar, Kutty Selva, Holmdahl, Rikard
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779414/
https://ncbi.nlm.nih.gov/pubmed/16813664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1989
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