Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis

INTRODUCTION: Cartilage oligomeric matrix protein (COMP) is a homopentameric protein in cartilage. The development of arthritis, like collagen-induced arthritis (CIA), involves cartilage as a target tissue. We have investigated the development of CIA in COMP-deficient mice. METHODS: COMP-deficient m...

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Main Authors: Geng, Hui, Carlsen, Stefan, Nandakumar, Kutty Selva, Holmdahl, Rikard, Aspberg, Anders, Oldberg, Åke, Mattsson, Ragnar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656236/
https://ncbi.nlm.nih.gov/pubmed/19014566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2551
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